The Complete Kidney Transplant Guide

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 The Complete Kidney Transplant Guide



A kidney transplant is the process of replacing one kidney with another from a living or deceased donor. The most common reason for receiving a kidney transplant is due to damage or disease of the existing kidneys that prevent them from functioning properly and thereby causing many of the vital organs to fail over time if they are not replaced in time. Kidney transplants are also performed to replace one diseased or damaged kidney with a new, healthy one as part of an organ swap program when both kidneys have been damaged by chronic disease, such as diabetes.


Background

A kidney transplant is a surgery to remove a diseased kidney and replace it with a healthy kidney from another person. The transplant operation usually takes four to six hours. A successful transplant depends on good matching between the donor and the recipient. The donated kidney can come from a deceased donor or a living donor. A living donor may be a relative, friend, or stranger. A successful transplant can mean many years of normal kidney function and improved quality of life for the recipient. Some recipients will never know they have had a transplant because there are no visible scars. After the surgery, patients need to take anti-rejection medicines for the rest of their lives in order to prevent rejection. 

A transplanted kidney comes from either a deceased donor or a living donor (typically someone related to you). A live donor needs less screening than an organ that comes from someone who has died due to the potential risk of infection. If you are interested in donating your own kidney, you must meet strict criteria set by various countries' legislation before going through with it; often this means providing two medical references attesting that you are not suffering any kind of mental disorder and undergoing tests for common blood-borne diseases such as HIV/AIDS and hepatitis B/C. In the United States, a prospective donor cannot donate a kidney if he or she is aware of having HTLV I/II (human T-cell lymphotropic virus), herpes simplex virus, cytomegalovirus, active syphilis, Chagas disease, hantavirus pulmonary syndrome or babesiosis. If a live donation does not work out due to these considerations then you might still be able to use organs obtained from brain dead donors where permission was given during life for the use of organs after death. Due to the limited supply of organs, some people find themselves waiting up to five years for a suitable match. For example, in 2013 over 150 000 Americans were waiting for an organ donation, but only 30000 became available. Of those receiving a transplant, 20% end up rejecting the new organ, while others experience complications such as infections and autoimmune disorders. After having a kidney transplant most people will go back to working full time within 6 months. However it is important to keep in mind that each case is different so your rehabilitation schedule could vary depending on other factors such as age and preexisting conditions like diabetes. The average lifespan following a kidney transplant ranges from 10-15 years with 95% of patients being alive after 5 years


Procedure

A kidney transplant is a surgery done to replace a diseased kidney with a healthy kidney from a donor. The new kidney will take over the work of filtering blood and removing waste from the body. Blood flows into one side of the new kidney, which filters out harmful toxins and produces urine on the other side. Blood then flows out through a small tube called an artery, while urine travels through another tube called a ureter before it leaves your body. 

Some people may need dialysis first before getting a transplant because their kidneys can't do their job on their own anymore (dialysis is used when your kidneys are not working well enough to remove wastes from your blood). Dialysis may be needed for up to three years before you get a transplant or until you find an appropriate donor. Once you have found an appropriate donor, you'll need to wait for that person's organ donation to become available, which could take anywhere from weeks to months. If the waiting time gets too long, your doctor might suggest continuing dialysis in order to prolong life until a suitable donor becomes available. When the time comes for surgery, you'll undergo general anesthesia so that you're asleep and unaware during the procedure. Your surgeon will insert a thin tube called a catheter through an incision in your upper chest area and into one of your large veins. The catheter has a deflated balloon attached at its tip; once it reaches the vein near your heart, air is pumped into the balloon so that it expands against this wall of tissue. With the balloon holding back blood flow in this area, doctors can make more room for inserting instruments like needles and catheters without bumping up against any major arteries along their way. They'll cut away some tissue around the diseased kidney to free it and connect it to the ureter coming from the new kidney. Next, they attach a length of tubing (called an arteriovenous graft) between two large blood vessels supplying each kidney: one called the superior vena cava (SVC) and one called inferior vena cava (IVC). Finally, they close off all connections except for those leading to IVC so that blood no longer flows through SVC. It's important that only IVC remains open because this vessel brings deoxygenated blood back to your heart--otherwise you wouldn't receive oxygenated blood via circulation--and maintaining this connection means you won't lose consciousness after surgery. As soon as the transplanted kidney starts producing urine, a stent will keep it connected to your bladder so that you don't have any accidents. For the first few days following surgery, you'll need help going to the bathroom. You may also experience nausea and vomiting, fever, chills and lightheadedness due to medication given during or after surgery. All these symptoms should go away within six weeks. In the meantime, you'll need to drink lots of fluids to avoid dehydration. Even though your new kidney should start working right away, it takes time for your blood chemistry to normalize and your body to adjust. Your doctor will prescribe anti-rejection drugs, which you'll take every day for the rest of your life. These drugs block certain substances from reaching the surface of the transplanted kidney, thereby stopping it from being rejected by your immune system. As a result, you'll be less likely to develop complications such as high blood pressure and bone loss that come with a suppressed immune system. However, there is a chance that your body will eventually develop antibodies to the anti-rejection medications, which would put you at risk for an acute rejection. The odds of this happening depend on how closely related the donor and recipient are and how much time passes before the first exposure to anti-rejection drugs. Fortunately, if you do end up with an acute rejection, it's usually possible to treat it with steroids or stop taking the medication altogether. Your doctor will advise you of the best course of action. Once in the patient's bladder, this fluid is released when they urinate.

The surgical team starts by stopping the flow of blood in your original kidneys. They then disconnect these organs from the urinary tract, stomach and intestine so that they can remove them safely without causing any damage to those organs. Next, they make an incision in your abdomen near where the kidneys are located and pull them out through this opening. Your new kidney should be placed at roughly a right angle to your original kidneys (usually behind them). A plastic tube called a catheter is inserted into each urna (one for each kidney) and used as a guide for attaching each end of the transplanted organ to either side of that tube inside you.


Health Benefits

A kidney transplant can have life-changing health benefits for people with kidney failure. It can improve or extend their life, and give them a better quality of life. People who have had a kidney transplant often feel better and have more energy. They may be able to return to work or school and enjoy their hobbies and activities again. In addition, people who have had a kidney transplant are less likelylikely to need dialysis treatments. Dialysis is when blood is cleaned outside the body using an artificial kidney (a machine). If you get a kidney transplant, you will no longer need dialysis. 

A person needs two kidneys to live, but only one is usually affected by disease. When the diseased kidney fails to work properly, it cannot filter waste from the blood effectively. The other healthy one does its best to compensate until it too begins to fail as well. But eventually both kidneys stop working altogether and require either dialysis or a transplant as treatment options. According to WebMD, Kidneys remove wastes and extra fluid from your body and make hormones that help regulate blood pressure. To start the process of getting a new kidney, go to your local hospital's nephrology department. The doctors there will take all of your medical history before performing lab tests on you. Afterwards they'll do an ultrasound test on your abdomen to see if you're eligible for a transplant. Most patients are asked to wait on the list because demand exceeds supply in many parts of the country so it could take months or years before receiving a new organ. And while waiting, they're encouraged to eat a diet low in protein and salt. As time goes on, some become too sick for surgery. They may need dialysis instead of a transplant. Other patients die waiting for transplants so it's important to maintain good health during this time period as much as possible. There are also risks involved with the procedure. Some people experience a severe reaction to medications called acute rejection which means their immune system has attacked the new kidney; though this is rare and there are drugs available to treat it. There is also risk of infection after surgery which can lead to sepsis, according to WebMD. Doctors must consider these risks carefully before deciding whether or not a patient should undergo such a procedure. Patients can also ask about stem cell therapy—another option in lieu of a traditional transplant. Stem cells are immature cells that turn into other types of cells like heart muscle, bone marrow and skin. Some countries offer these procedures already, but it is unclear what potential benefits might come from stem cell therapy for kidneys specifically at this point in time. However, researchers still believe stem cell therapy holds promise even without any clinical trials proving its effectiveness—making it worth exploring further studies. One recent study published in Nature showed how stem cells stimulated regeneration of multiple organs including the liver and pancreas as well as bladder tissue after cancer treatments--while another study found stem cells actually improved renal function when injected into mice with chronic kidney disease (CKD). After kidney transplant, most people are advised to avoid contact sports for a year or more. The transplant can sometimes cause the recipient to lose their sense of smell, taste and sex drive. A kidney transplant is a major operation and typically involves general anesthesia. This means the person will be asleep during the operation and unable to move, talk or breathe on their own. So before undergoing this procedure it's important to have a discussion with your doctor about the different complications that may arise. 

In conclusion, kidney transplant is a life-saving surgery when performed correctly. It can alleviate a person's symptoms of kidney failure and keep them living a long, healthy life. If you think you're experiencing signs of kidney disease, it's important to seek medical attention right away.


Surgery Risks and Complications

Before undergoing surgery, it's important to be aware of the risks and potential complications involved. Bleeding, infection, and blood clots are all possible complications of any surgery. When it comes to kidney transplant surgery specifically, there is also the risk that the body will reject the new kidney. If this happens, the patient will need to undergo further treatment to try to save the transplanted kidney. In some cases, a second transplant may be necessary. In addition to these risks, there are certain medical conditions which can increase the chances of complications during or after surgery: diabetes, heart disease, obesity, high blood pressure and high cholesterol. Smoking can have negative effects on the outcome as well - studies have shown that smoking in combination with kidney failure increases mortality rates by up to 50%. 

It's important for patients considering kidney transplant surgery to speak with their doctor about any conditions they might have before moving forward with the procedure. Generally speaking, if you're healthy enough to undergo general anesthesia and surgery without problems, you should be able to safely undergo kidney transplantation. After the procedure, most people experience an increased appetite and more energy due to better overall health. Patients who had trouble eating pre-surgery often find that they're hungry again post-surgery. Some medications may require changes following surgery as well; make sure your doctor knows what medications you take so he or she can help guide you through this process. One way to reduce risk factors is to maintain a healthy lifestyle and keep yourself at a normal weight. If you smoke, stop now! There are other ways to manage pain post-surgery including physical therapy, but it's always best not to ignore warning signs. Speak with your doctor right away if you experience fever, chills, vomiting or severe pain when urinating. Other symptoms include weakness, lightheadedness, chest pain and difficulty breathing. These could be signs of serious complication like a pulmonary embolism (blood clot in the lungs) or deep vein thrombosis (blood clot in the leg). Seek immediate medical attention if you suspect anything. As long as you don't have any pre-existing conditions, renal function shouldn't change after the transplant unless your medication needs change. The surgery itself takes between 2 and 4 hours under general anesthesia, followed by one week of recovery time. You'll go home once your doctors feel comfortable sending you home and once you're cleared for travel. You should be back to feeling normal within two weeks and ready to return to work within four weeks after surgery. Your insurance company should cover the cost of the surgery and, depending on the policy, may cover the cost of rehabilitation. The financial burden is generally minimal and varies depending on individual circumstances.

For those interested in donating their kidney to someone else, you'll need to be tested to see if you're a viable donor. Your blood type must match the recipient's type, and you must be free from infectious diseases such as HIV/AIDS and hepatitis B or C. You'll also need to answer questions about your own health status. Once approved as a donor, you'll be placed on the waiting list for compatible recipients along with other donors who meet eligibility requirements. If a matching donor is found, you'll undergo surgery to remove your kidney and transplant it into the person in need. You'll be expected to make a lifelong commitment to stay healthy and watch for any signs of kidney problems. Recipients can live relatively normal lives after transplant, though they may need to take immunosuppressant drugs for the rest of their lives. People who donate a kidney have a good chance of living longer than if they hadn't donated. However, there are risks associated with surgery and with going on immunosuppressant drugs for life, so this is something you should talk over with your doctor before deciding whether or not to donate your kidney. In addition, you'll need to avoid contact sports or activities with a high risk of injury, and you'll need to be screened for organ donation every few years. 

Performed on the same day as a kidney transplant, a pancreas transplant is a surgery in which the diseased pancreas is removed and replaced with a healthy pancreas from either the patient's father or another donor. A kidney-pancreas transplant is performed on the same day as both organs are removed together. A pancreas transplant may be recommended if your disease affects only your pancreas, or if you have diabetes and your diabetes cannot be controlled using other methods.


Cost of the Treatment

A kidney transplant is a major surgery with a lot of potential complications. The treatment itself is also very expensive. According to the National Kidney Foundation, the average cost of a kidney transplant in the United States is about $357,000. This includes the cost of the surgery, medications, and follow-up care. For people who do not have insurance, or who have insurance that does not cover transplant surgery, the cost can be even higher. These patients often need to pay for their medical care out-of-pocket, which can lead to financial problems for the patient and their family.

What are side effects? 

How long does it take? 

What happens after? After a kidney transplant surgery, most people will spend time in the hospital until they recover enough to go home. Most people will continue taking immunosuppressant drugs as well as other medications following their transplant. Patients may experience some side effects from these drugs, such as infections or high blood pressure. If any of these issues occur during your recovery period, you should contact your healthcare provider immediately so they can help you find solutions. It's important to stay on top of your health following a kidney transplant so you don't run into any complications down the line like scar tissue formation or an abnormal clotting disorder that may affect blood flow through your new kidneys. If you feel something isn't right, talk to your doctor right away. There are many reasons why someone would need a kidney transplant. In some cases, diseases like diabetes or hypertension damage the kidneys to the point where they no longer function properly. Other causes include polycystic kidney disease, polyarteritis nodosa, and lupus. But whether you're receiving a transplanted organ because of a chronic illness or due to injury sustained while serving in Iraq and Afghanistan, there's hope on the horizon with 3D printing technology advancements. Scientists at Wake Forest University (WFU) created bioink material made from cells, proteins, and a gelatin-like substance. Scientists can use this bioink to print skin grafts or organs - including human kidneys - without the need for another donor. Wake Forest scientists say that the new type of ink could allow doctors to create personalized body parts for transplant, matching both the size and compatibility of recipients. While we wait for this advancement to become available, here are 10 things you should know before getting a kidney transplant: 1. If you've never had one before, your chances of being called back by a surgeon who needs another kidney from a deceased donor increase if you sign up as an organ donor when applying for or renewing your driver's license; 2. Your age and general health status determine how quickly dialysis has to start after removal of both kidneys - usually within hours; 3. You must undergo dialysis treatments three times per week for life; 4. Kidney transplant is a life-saving procedure for people with kidney failure; 5. The transplant recipient's immune system does not reject the donor's kidney, meaning that the person can live a healthy and normal life; 6. Kidney transplant surgery requires a healthy, functioning kidney from a living donor who is a match with the recipient in terms of blood type and antibody sensitivities; 7. Medical costs for donors are covered by their insurance company - the procedure is safe and relatively simple; 8. People who receive kidneys from living donors typically have fewer complications than those who receive kidneys from deceased donors, although they need to take anti-rejection medications for life to keep their immune system from attacking the donated organ as foreign matter; 9. Doctors are able to place a kidney transplant in the body as soon as it's harvested from the donor, whereas a heart or lung transplant can take days to stabilize and heal; 10. If you want to be a living donor, your blood type and antibody sensitivities need to be compatible with the recipient's.


Other Considerations

Kidney transplantation is a life-saving treatment for end-stage renal disease, but it's not a cure. After a transplant, you'll need to take special care of yourself and your new kidney. In most cases, this means taking anti-rejection medications to suppress the immune system so that it doesn't attack the transplanted organ. These drugs are usually given in pill form, but they can also be delivered intravenously or by injection. You'll have blood tests every three months or so to make sure the medication is working properly. If the levels of certain proteins in your bloodstream go up too high, you may need to switch to another type of medication. And if your body rejects the new kidney (which happens when it starts attacking it), doctors will try other treatments like dialysis before going back on the list for another donor. 

In addition, some people who get a transplant develop problems with their body's clotting process because anti-rejection drugs cause an overproduction of antibodies that interfere with platelets and blood cells involved in clotting. For these patients, long term use of anticoagulant therapy such as warfarin (Coumadin) or aspirin is needed after surgery until they can adjust their dosage level through regular monitoring. Patients who receive living donor kidneys do not require lifelong therapy. Other potential risks include infection at the surgical site, stroke, and cancer caused by immunosuppressive agents. However, even though there are risks associated with getting a kidney transplant, there are also risks from chronic kidney failure or continuing dialysis - including death due to complications from those therapies themselves. 

Maintaining good health habits after your transplant - including healthy eating habits and proper exercise - can help prevent these additional risks. Learn more about what to expect following your transplant here. A kidney transplant is often considered a last resort treatment for end-stage renal disease, but it's not without its own risks. For example, the anti-rejection medications you'll need to take on a daily basis can increase your risk of developing a bleeding disorder called thrombotic thrombocytopenic purpura (TTP). There are also many different factors that could lead to your body rejecting the new kidney - which typically happens when it begins producing antibodies against the foreign tissue. Finally, some patients who receive transplants develop issues with blood clotting because of interference from immunosuppressants. The best way to reduce these and other post-transplant risks is simply by maintaining good health habits after your procedure. Healthy eating, plenty of exercise, and keeping your stress levels low are all important ways to ensure the safety of your new kidney. But the best defense against rejection, serious infections, bleeding disorders, and all other post-transplant complications is prevention. That means taking care to avoid unhealthy behaviors like smoking cigarettes or abusing alcohol. 

For a full list of advice to keep your new kidney healthy check out our article 12 Tips To Keep Your New Kidney Healthy. Learn More About Kidney Transplant. Click Here 

Now you know everything about kidney transplant.

Kidney transplant is a life-saving treatment for end-stage renal disease, but it's not a cure. After a transplant, you'll need to take special care of yourself and your new kidney. This includes anti-rejection medications to suppress the immune system so that it doesn't attack the transplanted organ, which can lead to complications like blood clotting and autoimmune diseases. As with any major surgery, however, there are risks - but even if you don't get a transplant, your health risks may still be substantial thanks to untreated or poorly managed chronic kidney failure or other complications from ongoing dialysis treatments.Kid ney transplant is a life-saving treatment for end-stage renal disease, but it's not a cure. After a transplant, you'll need to take special care of yourself and your new kidney. This includes anti-rejection medications to suppress the immune system so that it doesn't attack the transplanted organ, which can lead to complications like blood clotting and autoimmune diseases. As with any major surgery, however, there are risks - but even if you don't get a transplant, your health risks may still be substantial thanks to untreated or poorly managed chronic kidney failure or other complications from ongoing dialysis treatments.

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